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“Scientists Stunned by This Hidden Factor: The Real Reason You’re Terrible at Math Finally Revealed, and It’s Not Your Fault”

In a groundbreaking study that challenges conventional understanding, researchers have discovered that our brain's neurochemical balance, specifically involving the neurotransmitters GABA and glutamate, plays a pivotal role in determining mathematical proficiency, offering new insights into why some individuals effortlessly excel in math while others struggle.

Eirwen WilliamsEirwen WilliamsMay 23, 2025 at 8:37 AM6
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Illustration of neurotransmitters GABA and glutamate influencing mathematical proficiency. Image generated by AI.
Illustration of neurotransmitters GABA and glutamate influencing mathematical proficiency. Image generated by AI.
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IN A NUTSHELL
  • 🧠 Recent research highlights the significant role of neurotransmitters like GABA and glutamate in mathematical proficiency.
  • 📊 The study involved over 250 students, revealing a link between brain chemistry and math performance.
  • 🔄 As students age, the brain shifts from a GABA-dominated state to a glutamate-driven mode for optimized learning.
  • 🎓 Findings suggest educational strategies should align with neurochemical profiles to enhance learning outcomes.

Why do some people panic at the mere sight of an equation while others juggle numbers effortlessly? Although education, stress, and teaching methods are frequently cited, recent research unveils a surprising culprit lurking within our brains: our neurotransmitters. This discovery offers a fresh perspective on why around one in five people truly struggle with mathematics. The study highlights the chemical intricacies of the brain, specifically focusing on two neurotransmitters, GABA and glutamate, and their direct role in mathematical proficiency. Let’s delve into how these chemical messengers influence our mathematical abilities and what this means for the future of learning.

GABA, Glutamate, and Algebra

Approximately 20% of individuals face genuine challenges with mathematics. This struggle is often attributed to math anxiety, inadequate teaching methods, or cognitive disorders like dyscalculia. However, a groundbreaking study published in PLOS Biology introduces a more intimate explanation: our brain chemistry. Two crucial neurotransmitters, GABA and glutamate, are now believed to play a significant role in our comfort or discomfort with mathematics.

GABA, or gamma-aminobutyric acid, functions as an inhibitory neurotransmitter, calming neuronal activity and reducing stress. Conversely, glutamate is an excitatory neurotransmitter that enhances connections and boosts brain activity. The balance between these two chemicals is vital for learning, concentration, and memory. The study suggests that this balance might be a key factor in mathematical proficiency, highlighting a link between our brain’s chemistry and mathematical abilities.

An Extensive Study on Over 250 Students

The study followed 255 students from elementary school to university, measuring their mathematical abilities over two testing periods spaced approximately 18 months apart. During these periods, brain activity was monitored through imaging, focusing on a critical brain area: the left intraparietal sulcus (LIS), known for its role in numerical processing. The objective was to determine if a correlation exists between neurotransmitter concentrations in this area and mathematical performance, and how this relationship evolves with age.

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Researchers observed that younger participants with higher GABA levels in the LIS performed better in math tests, and these levels accurately predicted future performance. Interestingly, as students aged, those with elevated glutamate levels outperformed their peers. This suggests that as the brain matures, it shifts from a “calm” (GABA) to a “stimulated” (glutamate) mode to optimize mathematical learning.

A Changing Brain Dynamic Over Time

The findings are fascinating. In younger students, those with the highest GABA levels in the LIS excelled in math tests, and these levels could predict future success. Yet, in older students, the opposite was true: those with higher glutamate levels performed better. This indicates a shift in brain dynamics, where the brain transitions from a calm state facilitated by GABA to a more stimulated state driven by glutamate to enhance mathematical learning.

This evolving neurochemical balance suggests that mathematical performance is not solely dependent on motivation or teaching quality but also on a delicate, evolving neurochemical equilibrium. As the brain develops, understanding these shifts could revolutionize educational approaches, tailoring them to align with students’ neurochemical profiles.

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A New Way to Approach Learning

This discovery corroborates a crucial neuroscience hypothesis: the brain undergoes various “sensitive periods,” developmental windows during which it is more receptive to certain types of learning. For instance, language and motor coordination develop early, while complex cognitive skills like mathematics can continue to mature into adulthood. GABA and glutamate appear to play regulatory roles in this brain plasticity.

Can we enhance our neurotransmitters to become math prodigies? Not so fast. Although the study doesn’t provide a magic solution, it opens promising pedagogical avenues. Tailoring math education to match students’ brain development stages could enhance performance. A stressed and distracted child might benefit from a calming environment conducive to concentration (and potentially GABA production), whereas an adolescent or college student might thrive with more dynamic and stimulating methods.

And Now, What Do We Do?

These findings could also aid in understanding learning disorders like dyscalculia, which are often underdiagnosed. So, the next time you feel overwhelmed by an equation, don’t be too hard on yourself: perhaps your neurotransmitters are to blame! This research not only reshapes our understanding of learning difficulties but also challenges educational systems to consider neurochemical factors in teaching methodologies.

As we continue to unravel the complexities of the human brain, we must ask ourselves: How can we harness this knowledge to improve educational outcomes for all learners?

Our author used artificial intelligence to enhance this article.

Did you like it? 4.5/5 (24)

Educational Strategies Mathematical Innovation Neurological Research
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Eirwen Williams
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Eirwen Williams is a U.S.-based journalist at Visegrád Post, covering global news, politics, economics, science, culture, and society. A graduate of NYU’s Journalism Institute, she investigates the stories shaping today’s world — from international affairs and scientific advances to cultural movements and health trends. Her work brings sharp insight into the forces behind the headlines, from planetary challenges to everyday life and major sports events. Contact: [email protected]

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View 6 Comments
6 Comments
  1. Sylvester0 on May 23, 2025 3:38 AM

    Wow, I never thought my brain chemistry could be the reason I struggle with math! 🤯

    Reply
  2. cedrictranscendence on May 23, 2025 4:32 AM

    Does this mean I can blame my neurotransmitters for failing algebra? 😂

    Reply
  3. Sebastian on May 23, 2025 5:25 AM

    This is fascinating! Could this research be used to help people with dyscalculia?

    Reply
  4. john-paul on May 23, 2025 6:17 AM

    So, how do we test our GABA and glutamate levels? Asking for a friend. 😅

    Reply
  5. Ben on May 23, 2025 7:11 AM

    Wait, does this mean that teaching methods will change based on brain chemistry?

    Reply
  6. Elisa_resonance on May 23, 2025 8:03 AM

    Thanks for sharing this insightful article! I’ve always wondered why math was so hard for me.

    Reply
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